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Faculty
Pharmacology
Dr. Lokesh Kumar Bhatt
Associate Professor (M. Pharm, Ph.D.)
Dr. Lokesh Kumar Bhatt
Area of Specialization
Pharmacology, Toxicology & Therapeutics

Experience
Teaching: 12 years
Industry: 2 years

Interest areas
Molecular and Applied Pharmacology

Research
Publications – 42
Presentations- 10
Research projects- Completed- 05

Recent Publications
  • Gupta R, Bhatt LK, Johnston TP, Prabhavalkar KS. Colon Cancer Stem Cells: Potential target for the treatment of Colorectal Cancer. Cancer Biology & Therapy. 2019 May 3 [Epub ahead of print] (Impact factor: 3.1)
  • Shelat R, Bhatt LK, Khanna A, Chandra S. A comprehensive toxicity evaluation of novel amino acid-modified magnetic ferrofluids for magnetic resonance imaging. Amino Acids. 2019;51(6):929-943 (Impact factor: 2.9)
  • Sanchala D, Bhatt LK, Pethe P, Shelat R, Kulkarni YA. Anticancer activity of methylene blue via inhibition of heat shock protein 70. Biomed Pharmacother. 2018; 107: 1037-1045 (Impact factor: 3.4)
  • Sanchala D. Prabhavalkar K, Bhatt LK. Therapeutic approaches for the treatment of epidermal growth factor receptor mutated lung cancer. Current Cancer Drug Targets. 2018;18(8):773-791 (Impact factor: 2.6)
  • Shaikh S., Bhatt LK, Barve K., Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit. Phytomedicine. 2019; 55; 222-228 (Impact factor: 3.6)
  • Solanki A, Bhatt LK, Johnston TP, Prabhavalkar KS. Targeting Matrix Metalloproteinases for Diabetic Retinopathy: the way ahead? Curr Protein Pept Sci. 2019;20(4):324-333 (Impact factor: 2.8)
  • Solanki A, Bhatt LK, Johnston TP. Evolving targets for the treatment of atherosclerosis. Pharmacol Ther. 2018 187:1-12 (Impact factor: 10.6)
  • Choudhary N, Bhatt LK, Prabhavalkar KS. Experimental animal models for rheumatoid arthritis. Immunopharmacol Immunotoxicol. 2018 Jun;40(3):193-200 (Impact factor: 2.0)
  • Mandal A, Prabhavalkar KS, Bhatt LK. Gastrointestinal hormones in regulation of memory. Peptides. 2018 Apr;102:16-25 (Impact factor: 2.7)
  • Mokashi P, Bhatt LK, Khanna A, Pandita N. Swertisin rich fraction from Enicostema littorale ameliorates hyperglycemia and hyperlipidemia in high-fat fed diet and low dose streptozotacin induced type 2 diabetes mellitus in rats. Biomed Pharmacother. 2017, 96:1427-1437 (Impact factor: 3.4)
  • Kambli L, Bhatt LK, Oza M, Prabhavalkar K. Novel therapeutic targets for epilepsy intervention. Seizure. 2017; 51:27-34 (Impact factor: 2.8)
  • Lotankar S, Prabhavalkar KS, Bhatt LK. Biomarkers for Parkinson's Disease: Recent Advancement. Neurosci Bull. 2017, 33 (5): 585–597 (Impact factor: 3.1)
  • Menon N, Bhatt LK, Prabhavalkar K. Neuropeptides: a promising target for treating seizures. Neuropeptides. 2017; 65:63-70 (Impact factor: 2.9)
  • Bhounsule A, Bhatt LK, Prabhavalkar K, Oza M. Cyclin Dependent Kinase 5: A novel avenue for alzheimer’s disease. Brain Research Bulletin. 2017, 132: 28-38 (Impact factor: 3.4)
  • Sanchala D. Prabhavalkar K, Bhatt LK. Oncolytic Herpes Simplex Viral Therapy: A stride towards selective targeting of cancer cells. Front Pharmacol. 2017 8:270 (Impact factor: 3.6)
  • Bagwe SM, Kale PP, Bhatt LK, Prabhavalkar KS.Herbal approach in the treatment of pancytopenia. J Complement Integr Med. 2017;14(1)
  • Parkar NA, Bhatt LK, Veeranjaneyulu A. Efficacy of Nobiletin, a citrus flavonoid, in the treatment of cardiovascular dysfunction of diabetes in rats. Food Funct. 2016;7(7):3121-9 (Impact factor: 3.2)
  • Mishra R, Prabhavalkar K, Bhatt LK. Preparation, optimization, and evaluation of Zaltoprofen loaded microemulsion and microemulsion-based gel for transdermal delivery. J Liposome Res. 2016; 26(4):297-306 (Impact factor: 2.5)
  • Poovanpallil NB, Prabhavalkar K, Bhatt LK. Management of bipolar depression with Lamotrigine: an antiepileptic mood stabilizer. Front Pharmacol. 2015 Oct 23;6:242  (Impact factor: 3.6)
  • Bhatt, L.K, Addepalli, V. Matrix metalloproteinases in diabesity. Diabesity 2015, 1(2): 18-20
  • Bhatt LK, Veeranjaneyulu A. Inhibition of mmp-2 and mmp-9: a novel approach to prevent cardiovasculaar dysfunctions in type 2 diabetes. Endocrine practice. 2015; 21(No. 1) 10A (Impact factor: 3.2)
  • Bhatt LK, Veeranjaneyulu A. Potentiation of Matrix Metalloproteinase 2 & 9 inhibitory action of minocycline by aspirin: An approach to attenuate outcome of acute myocardial infarction in diabetes. Archives of Medical Research. 2014; 45(3):203-9 (Impact factor: 2.2)
  • Bhatt LK, Veeranjaneyulu A.   Targeting Matrix Metalloproteinase 2 and 9 for treatment of cardiovascular dysfunction of diabetes. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms. Ed. Turan B and Dhalla NS. Springer Wien, New York, USA 2014. pp 359-375
  • Bhatt LK, Veeranjaneyulu A.   Inhibition of Matrix Metalloproteinase 2 & 9 Ameliorate Parasympathetic Dysfunction Associated Impairment in Baroreflex and Chemoreflex in Diabetic Rats. Indian Journal of Pharmacology. 2013. Vol 45, Supplement S157 (Impact factor: 0.6)
  • Bhatt LK, Veeranjaneyulu A. Attenuation of Cardiac Autonomic Neuropathy and Left Ventricular Function by Inhibition of Matrix Metalloproteinase 2&9 in Diabetic Rats (Abstract). Circulation. 2012; 126: A18480 (Impact factor: 18.8)
  • Bhatt LK, Veeranjaneyulu A. Potentiation of Aspirin induced cerebroprotection by Minocycline: a therapeutic approach to attenuate exacerbation of transient focal cerebral ischemia. J Diab Vas Dis Res. 2012;9(1):25-34 (Impact factor: 3.3)
  • Bhatt LK, Veeranjaneyulu A. A therapeutic approach to treat cardiovascular dysfunction of diabetes. Exp Toxicol Pathol. 2012 Nov;64(7-8):847-53
  • Bhatt LK, Veeranjaneyulu A. Minocycline with Aspirin: An approach to attenuate diabetic nephropathy in rats. Renal Failure. Ren Fail. 2011;33(1):72-8. (Impact factor: 1.4)
  • Bhatt LK, Veeranjaneyulu A. Minocycline with aspirin: a therapeutic approach in the treatment of diabetic neuropathy. Neurol Sci. 2010;31(6):705-16. (Impact factor: 2.2)
  • Bhatt LK, Veeranjaneyulu A. Potentiation of Aspirin Induced Amelioration of Cardiovascular Dysfunction in Diabetic Rats by Minocycline. Circulation. 2010;122:A12934 (Impact factor: 18.8)
  • Bhatt LK, Veeranjaneyulu A. Potentiation of aspirin induced cardioprotection by minocycline against myocardial ischemia reperfusion injury in streptozotocin diabetic rat (abstract). FASEB J. 2010 24:572.4 (Impact factor: 5.5)
  • Bhatt LK, Veeranjaneyulu A. Attenuation of diabetic retinopathy by enhanced inhibition of MMP-2 and MMP-9 using aspirin and minocycline in streptozotocin-diabetic rats. Am J Transl Res, 2010;2:181-189 (Impact factor: 3.0)
  • Bhatt LK, Bansal J, Piplani P, Bodhankar SL, Veeranjaneyulu A. Cardioprotective and ß-adrenoceptor antagonistic activity of a newly synthesized aryloxypropanolamine derivative PP-36. J Exp Pharmacol. 2010 , 2: 37-45 (Impact factor: 3.2)
  • Bhatt LK, Veeranjaneyulu A. Reversal of altered vasculature by MMP-2 & MMP-9 inhibition: an approach to reduce outcome of ischemic stroke in diabetic rats (Abstract). Diabetes, 2009, 58 (suppl 1,): 723-P (Impact factor: 7.2)
  • Bhatt LK, Veeranjaneyulu A. Enhanced MMP-2 and MMP-9 inhibition: An approach to treat diabetic nephropathy. J Clin Pharmacol. 2009, 9: 1111 (Impact factor: 3.1)
  • Dhaneshwar SS, Gairola N, Kandpal M, Vadnerkar G, Bhatt LK, Rathi B, Kadam SS. Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease. Eur J Med Chem. 2009 (10):3922-9  (Impact factor: 4.8)
  • Bhatt LK, Veeranjeneyulu A. Reversal of altered vascular reactivity and vascular structure in diabetic rats by the combination of minocycline and aspirin. . Indian J Pharmacol. 2008; 40 (Suppl 2): S107 (Impact factor: 0.6)
  • Veeranjeneyulu A, Bhatt LK. Minocycline with aspirin, a new therapeutic approach for the treatment of diabetic neuropathy in Rats. Indian J Pharmacol. 2008; 40 (Suppl 2): S98 (Impact factor: 0.6)
  • Bhatt LK, Nandakumar K, Bodhankar SL, Bansal J, Piplani P. Beta-blocking activity of PP-34, a newly synthesized aryloxypropanolamine derivative, and its cardioprotective effect against ischaemia/reperfusion injury in laboratory animals.  J Pharm Pharmacol. 2007, 59(3): 429-36 (Impact factor: 2.1)
  • Nandakumar K, Bhatt LK, Bansal S, Bodhankar SL, Ghole VS, Coumar MS, Jindal DP. Cardioprotective effect of newly synthesized acyl amino substituted propanolamine derivatives, DPJ 890 and DPJ 955 against isoprenaline induced myocardial necrosis. Toxicol Int, 2005, 12(2): 61-66
  • Gupta P, Pate N, Bhatt LK, Zambare GN, Bodhankar SL, Nandakumar K. Anti-urolithiatic Effect of Petroleum Ether Extract Stem Bark of Crataeva adansonii DC. in Rats. Pharm Biol, 2006, 44(3), 160-165 (Impact factor: 1.8)
  • Bhatt LK, Nandakunar K, Bodhankar SL. Experimental animal models to induce cardiac arrhythmias. Indian J Pharmacol, 2005, 37(6), 348-357 (Impact factor: 0.6)

Awards
  1. Metabolic Endocrine Education Foundation (MEFF), California, USA awarded grant for presenting a paper at 12th World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease” held on 20-22nd Nov 2014 at Los Angeles, California, USA
  2. Department of Science and Technology (DST), India awarded travel grant of Rs 1,00,000/- for presenting a paper at 12th World Congress on Insulin Resistance Diabetes and Cardiovascular Disease, California, USA, November 2014.
  3. American Heart Association’s Award:  American Heart Association awarded US$ 2000 for presenting a paper at Scientific Sessions at Los Angeles, USA, November 2012.
  4. Indian Council of Medical Research (ICMR) has awarded travel grant of Rupees 1,00,000/- for attending AHA (American Heart Association) Scientific session, Los Angeles, USA.
  5. ASPET Travel Grant:  American society of Pharmacology and Experimental Therapeutics Awarded travel grant for presenting present paper at ASPET annual meeting, Experimental Biology, April 2010, Anaheim, CA, USA. (This award has been funded from the I. C. Winter Fund.)
  6. Barrie Hesp Award: Awarded US$ 1000 for paper presented at Keystone Symposia:  Complication of Diabetes and Obesity, March 2009, Vancouver, Canada.
  7. All India Council for Technical Education (AICTE) has awarded travel grant for attending Keystone Symposia: Complication of Diabetes and Obesity, March 2009, Vancouver, Canada.


E-mail (O)- lokesh.bhatt@bncp.ac.in

Tel. 022 42332079