Dr. Vasanti Suvarna

Assistant Professor (M. Pharm)

Specialization: Pharmaceuticalchemistry & Quality Assurance

Experience: 

Teaching: 13 years 

Industry: 02 Years 

Thrust research areas: Naturalproduct chemistry, analytical method development 

Research Publications: 33

Presentations: 14

Book chapters: 02 

Research Sanctioned Projects:Completed- 02 (University of Mumbai minor research grant

Research students guided M.Pharm- 13

Conferences/ Seminars/ Workshops attended 20 

Recent Publications:

o    Sumit S. Vakani,  Apeksha Kajwe, VasantiSuvarna,  Atul P. Sherje, Influence of auxiliary agents on solubility anddissolution profile of repaglinide with hydroxypropyl-b-cyclodextrin: inclusioncomplex formation and its solid-state characterization. J Incl Phenom MacrocyclChem (2015) 83:239–250.

o    Suvarna, V., Sarkar, M., Chaubey, P., Khan, T.,Sherje, A., Patel, K., & Dravyakar, B. (2018). Bone Health and NaturalProducts- An Insight. Frontiers in pharmacology, 9, 981. (Frontierspublications)

o    Suvarna, Vasanti, Manikanta Murahari, TabassumKhan, Pramila Chaubey, and Preeti Sangave. "Phytochemicals and PI3KInhibitors in Cancer—An Insight." Frontiers in pharmacology 8(2017).(Frontiers publications).

o    Suvarna, Vasanti, Siddhata Thorat, Usha Nayak,Atul Sherje, and Manikanta Murahari. "Host-guest interaction study ofEfavirenz with hydroxypropyl-ß-cyclodextrin and l-arginine by computationalsimulation studies: Preparation and characterization of supramolecularcomplexes." Journal of Molecular Liquids 259 (2018): 55-64.(Elsevier publications)

o    Suvarna, Vasanti M., and Preeti C. Sangave."HPLC Estimation, Ex vivo Everted Sac Permeability and In VivoPharmacokinetic Studies of Darunavir." Journal of chromatographicscience (2018).(Oxford press publications)

o    Patel, K., Butala, S., Khan, T., Suvarna, V.,Sherje, A., & Dravyakar, B. (2018). Mycobacterial siderophore: A review onchemistry and biology of siderophore and its potential as a target fortuberculosis. European journal of medicinal chemistry.(Elsevier  publications)

o    Dravyakar, B. R., Khedekar, P. B., Khan, T.,Sherje, A. P., Patel, K. N., & Suvarna, V. (2018). Design and Developmentof Novel 2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as SelectiveCOX-II inhibitor. Anti-inflammatory & anti-allergy agents in medicinalchemistry. (Bentham publications).

o    Tabassum Khan, Kaksha Sankhe, Vasanti Suvarna,Atul Sherje, Kavitkumar Patel, Bhushan Dravyakar. DNA gyrase inhibitors:Progress and synthesis of potent compounds as antibacterial agents. Biomedicine& Pharmacotherapy 103 (2018) 923–938. (Elsevier publications)

o    Sherje, Atul P., Manikanta Murahari, VasantiSuvarna, and Kavitkumar Patel. "Study on effect of L-arginine onsolubility and dissolution of Zaltoprofen: Preparation and characterization ofbinary and ternary cyclodextrin inclusion complexes." Chemical Physics Letters (2018).(Elsevierpublications)

o    Chaubey, Pramila, Brahmeshwar Mishra, Shyam LalMudavath, Ravi R. Patel, Sundeep Chaurasia, Shyam Sundar, Vasanti Suvarna, andMarvis Monteiro. "Mannose-conjugated curcumin-chitosan nanoparticles:Efficacy and toxicity assessments against Leishmania donovani." International journal ofbiological macromolecules (2018). (Elsevier publications)

o    Suvarna V, Gujar P, Murahari M. Complexation of Phytochemicals withCyclodextrin derivatives – An Insight, Biomedicine & Pharmaco-therapy.  2017 Feb 12; 88:1122-1144.(Elsevier publications)

o    Vasanti Suvarna & Apeksha Kajwe &Manikanta Murahari & Guru basavaraj V. Pujar & Bharath Kumar Inturi& Atul P. Sherje. Inclusion complexes of Nateglinide with HP-ß-CD andL-arginine for solubility and dissolution enhancement: Preparation,characterization and molecular docking study Journal of Pharmaceuticalinnovation. June 2017, Volume 12, Issue 2, pp 168–181.(Springerpublications)

o    Sherje AP, Kulkarni V, Murahari M, Nayak UY, Bhat P, Suvarna V, Dravyakar B. Inclusion Complexation of Etodolac withHydroxypropyl-beta-cyclodextrin and auxiliary agents: Formulationcharacterization and Molecular modeling studies, Molecularpharmaceutics,  2017, 14 (4), pp 1231–1242 (American chemical societypublications)

o    Suvarna V, Singh V, Murahari M. Current overviewon the clinical update of Bcl-2 anti-apoptotic inhibitors for cancer therapy.European Journal of Pharmacology. 2019 Sep 5:172655.

o    Murahari M, Singh V, Chaubey P, Suvarna V*. ACritical Review on Anticancer Mechanisms of Natural Flavonoid Puerarin.Anti-cancer Agents in Medicinal Chemistry. Volume 20 , Issue 6 , 2020, p-678 -686. (Bentham publications)

o    Adishri Raut, Dhvani Sharma & VasantiSuvarna (2020), A Status Update on Pharmaceutical Analytical Methods ofAminoglycoside Antibiotic: Amikacin,      Critical Reviews in Analytical Chemistry, DOI: 10.1080/10408347.2020.1803042(Taylor francis publications)

o    Vasanti S, Shrutika P, N.D Grampurohit“Evaluation of Antibacterial and Antifungal Activities Zingiber Cassumunar Roxb.” Asian journal of microbiologybiotechnology & environmental sciences, 2008(3).

o    Vasanti S, Shrutika P “Antimicrobial activity ofclove essential oil against    clinical dental isolates"Asian journalof microbiology biotechnology & environmental sciences. Vol.11, No.(1), 2009: 137-138.

o    Vasanti S, “Synthesis of N-acyl heterocyclesusing conventional and microwave-assisted dry media technique” Journal of Pharmacy andresearch. October 2008 (1), Issue 2, Page no.240-.244.

o    Vasanti S, Sulabha S Impurity profile- A review.Drug Invention Today 2009, 1(2),81-88

o    Vasanti S, Sulabha S, Aabha C.“Bioceramics”,  Journal of Pharmacy and research, Vol 2, No 10 (2009).

o    Suvarna Vasanti,  “Evaluation ofantimicrobial activity of plant extracts” IJPSR, 2015; Vol. 6(4): 1547-1552

o    Vasanti S, Preeti S. Paclitaxel Nanoparticles -An Approach to Improve the Bioavailability  Int. J. Pharm. Sci. Rev. Res.,27(1) , July August 2014, 200-208.

o    Vasanti S, In-Vitro Cytotoxic Activity ofMethanolic Extract of Embelia tsjeriam Cottam, against Human Breast and ColonCancer Cell Lines.  Research Journal of Pharmaceutical, Biological andChemical Sciences. 5(5), September - October 2014, 131.

o    Mohammed Sajid, Utkarsha Pagdhare and VasantiSuvarna, Pharmacological evaluation and development of an antiulcer polyherbalformulation. World journal of pharmacy and pharmaceutical sciences Vol 4, Issue05, 2015.

o    Kadam N. R. and Suvarna V, Microspheres: a briefreview, Asian Journal of Biomedical and Pharmaceutical Sciences, 5(47), 2015,13-19.

o    Lalit Rathod, Vasanti Suvarna and Neha k.Shinde, Development and validation of a stability indicating RP-HPLC method forsimultaneous determination of acetylcysteine and cefixime in pharmaceuticalformulation. IJPSR (2015), vol. 6, issue 11.

o    Vasanti Suvarna, Utkarsha Paghadre, Anila Kadu,Manisha Oza "Development and characterization of solid self-emulsifyingdrug delivery system containing nateglinide" Asian Journal ofPharmaceutics.  2017 Mar 21;11(01).

o    Yunus Y. Khan, Vasanti Suvarna, Liposomescontaining phytochemicals for cancer treatment-an update, International Journalof Current Pharmaceutical Research,Vol 9, Issue 1, 2017.

o    Parinaz F. Elavia *, Vasanti Suvarna, A reviewon applications of nanotechnology in cosmetics, Int. Res. J. Pharm. 2018, 9 (4)

o    Suvarna, V. M., & Sangave, P. C. (2017).Development and validation of stability indicating RP-HPLC method for tenofovirsolid lipid nanoparticles. International Journal of Pharmaceutical Sciencesand Research, 8(2), 658-666.

o    Vasanti S, Shrutika P “Antifungal activity ofselected plant extracts against human fungal pathogens” Journal of Herbal medicine andtoxicology, 3(2) 151-153, (2009).

Professionalmembership

·        Life member of Indian PharmaceuticalAssociation (IPA)

·        Life member of Indian Society for Technical Education(ISTE) 

Contact:

Vasanti.suvarna@bncp.ac.in

Tel. (O): 022- 4233 2052 (Ext. 2110)

Dr. Atul P. Sherje

Assistant Professor (M. Pharm. Ph. D.)

Specialization:Pharmaceutical Chemistry Quality Assurance 

Experience: Academic:15 Years

Thrust research areas: Developmentand Validation of analytical methods Solubility enhancement of poorly water-solubledrugs 

Publications / Presentations:Research Review Publications: 31

Presentations: 16 

Books / Bookchapters: Nil 

Conferences /Workshops / Seminar Attended 35 

Research /Sponsored: 

Projects: Two (Completed) 

Research Students: M. Pharm. 13 (Completed); 1 (ongoing) 

Recent Publications:

•        Shradha Bodkhe, Mayuri Nikam,Atul P.Sherje, Tabassum Khan, Vasanti Suvarna, Kavit Patel. Current Insights onClinical Efficacy of Roflumilast for Treatment of COPD, Asthma and ACOS.International Immunopharmacology (2020), 88, 106906. 

•        Sohini Bhattacharya, Atul P. Sherje;Development of Resveratrol and Green Tea Sunscreen Formulation for CombinedPhotoprotective and Antioxidant Properties. Journal of Drug Delivery Scienceand Technology (2020), 60, 102000.

•        AP Sherje, A Surve, P Shende. CDIcross-linked ß-Cyclodextrin nanosponges of Paliperidone: Synthesis andphysicochemical characterization, Journal of Materials Science: Materials inMedicine (2019), 30, 6, 74.

•        Bhushan R. Dravyakar*, Pramod B. Khedekar,Tabassum Khan, Atul P. Sherje,Kavit N. Patel, Vasanti Suvarna. Design and Development of Novel2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as Selective COX-IIInhibitor, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry(2019), 18, 1-22.  

•        Jeevankala S. Tople, Atul Sherje, RashmiMallya. Analytical method development and validation for simultaneousdetermination of pyrantel pamoate and febantel in an oral dosage form byhigh-performance liquid chromatography (HPLC). International Journal ofPharmaceutical Sciences and Research (2019), 10, 4, 1747-1752. 

•        Neha Desai, Munira Momin, Upasana Singh,Tabassum Khan, Atul Sherje. Analytical method development and validation forsimultaneous estimation of curcumin and cyclosporine by RP-HPLC. InternationalJournal of Pharmacy and Pharmaceutical Sciences (2019), 11, 2, 26-33. 

•        Sherje A, Sonalkar A, Forceddegradation studies of olmesartan medoxomil and chlorthalidone: development andvalidation of stability-indicating RPHPLC method, Indian Drugs (2019), 56, 3,39-45. 

•        Atul P. Sherje, Mrunal Jadhav,ß-Cyclodextrin-based inclusion complexes and nanocomposites of rivaroxaban forsolubility enhancement. Journal of Materials Science: Materials in Medicine(2018), 29, 186.

•        Kavitkumar Patel, Sahil Butala, TabassumKhan, Vasanti Suvarna, Atul Sherje,Bhushan Dravyakar. Mycobacterial siderophore: A review on chemistry and biologyof siderophore and its potential as a target for tuberculosis. European Journalof Medicinal Chemistry (2018), 157, 783-790. 

•        Atul P. Sherje, Mrunal Jadhav, Bhushan R.Dravyakar, Darshana Kadam. Dendrimers: A versatile nanocarrier for drugdelivery and targeting. International Journal of Pharmaceutics (2018), 548,1,  707-720. 

•        Tabassum Khan, Kaksha Sankhe, VasantiSuvarna, Atul Sherje, Kavitkumar Patel, Bhushan Dravyakar. DNA gyraseinhibitors: Progress and synthesis of potent compounds as antibacterial agents.Biomedicine and Pharmacotherapy (2018), 103,  923–938.

•        Atul P. Sherje, Forum Patel, ManikantaMurahari, Vasanti Suvarna, Kavitkumar Patel, Study on Effect of L-Arginine onSolubility and Dissolution of Zaltoprofen: Preparation and Characterization ofBinary and Ternary Cyclodextrin Inclusion Complexes, Chemical Physics Letters(2018), 694, 120-128. 

•        Atul P. Sherje, Vaishali Londhe.Development and Evaluation of pH-Responsive Cyclodextrin-Based in situ Gel ofPaliperidone for Intranasal Delivery. AAPS PharmSciTech (2018), 19, 1,384–394. 

•        Atul P. Sherje, Bhushan R. Dravyakar,Darshana Kadam, Mrunal Jadhav, Cyclodextrin-based nanosponges: A criticalreview, Carbohydrate Polymers (2017), 173 37–49. 

•        Sherje Atul, Kulkarni Vaidehi,Murahari Manikanta, Nayak Usha, Bhat Pritesh, Suvarna Vasanti, DravyakarBhushan. Inclusion Complexation of Etodolac withHydroxypropyl-beta-cyclodextrin and auxiliary agents: Formulationcharacterization and Molecular modeling studies. Molecular Pharmaceutics(2017), 14, 1231-1242. 

•        Vasanti Suvarna, Apeksha Kajwe, ManikantaMurahari, Gurubasavaraj V. Pujar, Bharath kumar Inturi, AtulSherje, Inclusion complexes of Nateglinide with HP-ß-CDand L-arginine for solubility and dissolution enhancement: Preparation,characterization and molecular docking study. Journal of PharmaceuticalInnovation (2017), 12, 2, 168–181. 

•        Sumit Vakani, Apeksha Kajwe, VasantiSuvarna, Atul P. Sherje. Influence of Auxiliary Agents on Solubility andDissolution Profile of Repaglinide with Cyclodextrin: Inclusion ComplexFormation and its Solid-state Characterization, Journal of Inclusion Phenomenonand Macrocyclic chemistry (2015), 83, 3, 239-250. 

•        Atul P. Sherje, Vaishali Londhe.Ternary Inclusion Complex of Paliperidone with ß-Cyclodextrin and HydrophilicPolymer for Solubility and Dissolution Enhancement. Journal of PharmaceuticalInnovation (2015), 10, 4), 324-334.  

•        Sherje A, Londhe V. Inclusion Complexes ofHydroxypropyl-beta-Cyclodextrin and Paliperidone: Preparation andCharacterization, Current Drug Discovery Technologies (Springer), 2014, 11,271-278. 

•        Sherje AP, Kasture AV, Yeole PG,“Simultaneous spectrophotometric determination of lansoprazole and domperidonein capsule formulation”, Asian Journal of chemistry, 19 (5), 2007,3612-3616. 

•        Atul P. Sherje,Vaishali Londhe. StabilityIndicating HPLC method for determination of Paliperidone in Bulk. InternationalJournal of PharmTech Research (2015), 8, 8, 157-163.

•        SP Dhat, SA Aphale,AP Sherje, JA Sakale, AVVaidya, SD Vanshiv, Solubility enhancement of Satranidazole using soliddispersion technique, International Journal of Research in Pharmaceutical andBiomedical Sciences (2011), 2, 3, 1134-1138.

•        Sherje A.P., Desai KJ; Spectrophotometricdetermination of Rosiglitazone Maleate using Hydrotropic solubilizationtechnique, Indian Journal of Pharmaceutical Sciences (2011), 73, 5, 579-582.

•        Sherje A.P., Chokshi J, Satam CA, ChaudharyD, Vanshiv SD, Spectrophothometric Determination of Nitazoxanide and Ofloxacinin Combined Dosage Form, Journal of Pharmacy Research (2010), 3, 1,72-74. 

•        Sherje AP, Tawade AP, Vyas M, SimultaneousSpectrophotometric Determination of Satranidazole and Ofloxacin in CombinedDosage Form, International Journal of PharmTech Research (2010), 2, 1,511-514. 

•        Sherje AP, Rahigude A, Vanshiv SD, Warma S,Mixed Hydrotropy in Spectrophotometric Analysis of Nitazoxanide, InternationalJournal of ChemTech Research (2010), 2, 4, 1966-1969. 

•        Sherje A.P., Yeole PG, Puranik MP, MominMY, “In-vitro evaluation of Government hospital supplied and commercial brandsof Paracetamol”, Indian Journal of Pharmaceutical Education (2005), 39, 1.

•        Sherje A.P., Kasture AV, Yeole PG,“Simultaneous quantitation of lansoprazole and domperidone in pharmaceuticalformulations by liquid chromatography”, Journal of Pharmaceutical Research(2009), 8, 1, 52-55. 

•        Sherje A.P., Gujar KN, Bidkar AA,“Phytochemical and Pharmacological investigation of leaves of Calotropisprocera Linn” Journal of Natural Remedies (2009), 9, 1, 79—84. 

•        Vanshiv Swapnila, Joshi Hemant, SherjeAtul, Aphale Sanjivani, Dhat Shalaka.  Gastroretentive DrugDelivery System: Review, Journal of Pharmacy Research (2009), 2, 12,1879-1885. 

•        Sherje A.P., Kasture AV, Gujar KN, YeolePG, “Simultaneous spectrophotometric determination of lansoprazole anddomperidone in capsules” Indian Journal of Pharmaceutical Sciences (2008), 70,1, 102-105.

ProfessionalMemberships:

Life Member of Association of Pharmaceutical Teachers of India (APTI)

Life member of Indian Society for Technical Education (ISTE) 

Contact:

E-mail: atul.sherje@bncp.ac.in

Tel. (O). 022- 4233 2052 (Ext. 2163)

Dr. Kavitkumar N. Patel

Assistant Professor (M. Pharm.Ph.D.)

Specialization:
Pharmaceutical Chemistry / Medicinal Chemistry

Experience:
Academics: 5 Years

Thrust Research Areas:
Medicinal Chemistry, Organic Chemistry, Computer Aided Drug Design; Drug designand synthesis of anti-tubercular and antibacterial drugs.

Publications/ Presentations:
Publications: 14
Presentations: 06

Recent Publications:
Shradha Bodkhe, Mayuri Nikam, Atul P. Sherje, Tabassum Khan, Vasanti Suvarna,Kavit Patel; Current insights on clinical efficacy of roflumilast for treatmentof COPD, asthma and ACOS; InternationalImmunopharmacology 88 (2020)106906. (IF-3.943)

• Dravyakar BR, Khedekar PB, Khan T, Sherje AP, Patel KN, Suvarna V.Design and Development of Novel 2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as Selective COX-II Inhibitor. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2019; 18(1), 4-25.
• Vasanti Suvarna*, Megha Sarkar, Pramila Chaubey, Tabassum Khan, Atul Sherje, Kavitkumar Patel and Bhushan Dravyakar; Bone Health and Natural Products- An Insight; Frontiers in Pharmacology 2018; Volume 9, Article 981. (IF-3.831)
• Kavitkumar Patel*, SahilButala, Tabassum Khan, Vasanti Suvarna, Atul Sherje, Bhushan Dravyakar, Mycobacterial siderophore: A review on chemistry and biology of siderophore and its potential as a target for tuberculosis, European Journal of Medicinal Chemistry 157 (2018) 783-790. (IF-4.816)
• K. Tabassum, P. Ekta, P. Kavitkumar; Imidazole and Pyrazole: Privileged Scaffolds for Anti-Infective Activity; Mini-Reviews in Organic Chemistry (2018) 15 (6) 2018, 459 - 475. (IF-1.095)
• Tabassum Khan, KakshaSankhe, Vasanti Suvarna, Atul Sherje, Kavitkumar Patel, Bhushan Dravyakar; DNA gyrase inhibitors: Progress and synthesis of potent compounds as antibacterial agents, Biomedicine & Pharmacotherapy (2018) 103, 923–938. (IF-2.759)
• Atul P. Sherje, Forum Patel, ManikantaMurahari, Vasanti Suvarna, Kavitkumar Patel, Study on Effect of L-Arginine on Solubility and Dissolution of Zaltoprofen: Preparation and Characterization of Binary and Ternary Cyclodextrin Inclusion Complexes” Chemical Physics Letters (2018) 694, 120-128. (IF-1.815)
• Kavitkumar N. Patel, Vikas N. Telvekar*; Design,    synthesis   and antitubercular evaluation of        novel      series of N-[4-(piperazin-1-yl)phenyl]cinnamamide derivatives; European Journal of Medicinal Chemistry (2014) 75, 43-56.
• Kavitkumar N. Patel, Nikhil C. Jadhav, Prashant B. Jagadhane, Vikas N. Telvekar*; An expedient route to the azoles through oxidative desulfurization using iodine reagent; Tetrahedron Letters (2013), 54 (1), 101–105.
• Kavitkumar N. Patel, Nikhil C. Jadhav, Prashant B. Jagadhane and Vikas N. Telvekar*; A novel strategy for construction of azole heterocycles via oxidative desulfurization approach using iodobenzene and Oxone®; Synlett (2012), 23 (13), 1970–1972.
• Vikas N. Telvekar*, Kavitkumar N. Patel; Pharmacophore Development and Docking Studies of the HIV-1 Integrase Inhibitors Derived from N-methylpyrimidones, Dihydroxypyrimidines, and Bicyclic Pyrimidinones; Chemical Biology and Drug Design (2011), 78 (1), 150–160.
• Vikas N. Telvekar*, Kavit N. Patel, Harish S. Kundaikar, Hemchandra K. Chaudhari; A novel system for the synthesis of nitriles from aldehydes using aqueous ammonia and sodium dichloroiodate; Tetrahedron Letters (2008), 49 (14), 2213-2215.
• Vikas N. Telvekar*, Harish S. Kundaikar, Kavit N. Patel, Hemchandra K. Chaudhari; 3D-QSAR and Molecular Docking Studies on Aryl Benzofuran-2-yl ketoxime derivatives as Candida albicans N-Myristoyltransferase Inhibitors, QSAR and Combinatorial Science (2008), 27 (10), 1193-1203.
• J. K. Joshi*, V. R. Patel, K. N. Patel, D. Rana, K. A. Shah, R. D. Patel, R. Patel, Synthesis and Anti-inflammatory activity of N-arylanthranilic acid and its derivatives, Indian Journal of Pharmaceutical Science (2007), 69 (5), 697-699.

Awards:
Awarded with Junior Research Fellowship (JRF) and Senior Research Fellowship(SRF) from University Grant Commission (UGC), Government of India for pursuingPh.D.
Awarded travel grant by DST and ICMR to attend Tetrahedron Symposium in Vienna,Austria 2013.

Conferences/ Workshops/ Seminars attended: 20

Contact details:
E-mail: kavitkumar.patel@bncp.ac.in

Tel. (O): 022-4233 2052 (Ext. 2060)