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Drug Development facility

The Drug Discovery & Development Facility is designed to promote the design, discovery and development of new drugs through multi-disciplinary research involving chemistry, medicinal chemistry, pharmaceutics, pharmaceutical technology and biology. The architecture provides facilities for computer-aided drug design, computational pharmaceutics, organic synthesis, molecule purification and characterization as well as in vitro and in vivo biological screening.

  • Computer-aided drug design and development
  • Target-based / Ligand-based / Cheminformatics-based drug designing
  • In-silico ‘Knock-out’ / Mutation studies
  • Lead optimization (binding affinity, selectivity, off-target effects, solubility enhancement)
  • In-silico formulation development studies
  • Chemical synthesis and characterization of novel chemical entities
  • API and API intermediate synthesis
  • Impurity synthesis (in collaboration with Indian Pharmacopoeia Commission)
  • Formulation development of Novel Nanotechnology based Herbal and Nutraceutical Products
  • Standardization of herbal extracts, herbal and nutraceutical products (AYUSH products)
  • Cell line studies of API, Finished products, Herbal extracts, phytoconstituents
  • Anticancer bioassays
  • Cytotoxicity assays